Certain items not printing on Layout

[AMTDESIGN]

Using V 6 beta,I had a few occasions where items on layout sheets were simply not printing. Long time user here, familiar with all the routine of printing from layout. At first in Beta it was PDF imports not printing even though they were clearly inside the layout sheet etc. I figured it was Beta and an import so that there is just a quirk to work out. Upgraded to V 6 the other day. Now an image of an overview sent directly to layout is not printing ,again even though it is one of several on the layout sheet. The entire layout border etc. print fine, as do the other items on the sheet, its just a big blank hole in the middle of the layout sheet. Anyone else experiencing this? I closed it out, reopened it,reprinted it and the same image did not print. Is this a bug? Thanks all.